Updated for 2026
Verified open hours, holiday schedules, and savings programs for 7 major US pharmacy chains across 50 states and 103+ cities.
9,000 US locations · founded 1963
Monday–Friday 9:00am–9:00pm, Saturday 9:00am–6:00pm, Sunday 10:00am–6:00pm
View CVS hours →8,500 US locations · founded 1901
Monday–Friday 8:00am–10:00pm, Saturday 9:00am–6:00pm, Sunday 10:00am–6:00pm
View Walgreens hours →1,700 US locations · founded 1962
Monday–Friday 9:00am–9:00pm, Saturday 9:00am–6:00pm, Sunday 10:00am–6:00pm
View Rite Aid hours →4,600 US locations · founded 1978
Monday–Friday 9:00am–7:00pm, Saturday 9:00am–7:00pm, Sunday 10:00am–6:00pm
View Walmart Pharmacy hours →540 US locations · founded 1983
Monday–Friday 10:00am–7:00pm, Saturday 9:30am–6:00pm, Sunday closed
View Costco Pharmacy hours →2,200 US locations · founded 1883
Monday–Friday 9:00am–9:00pm, Saturday 9:00am–6:00pm, Sunday 11:00am–5:00pm
View Kroger Pharmacy hours →1,300 US locations · founded 1986
Monday–Friday 9:00am–9:00pm, Saturday 9:00am–7:00pm, Sunday 11:00am–6:00pm
View Publix Pharmacy hours →Will the pharmacy be open? Here's what every chain does on the major US holidays.
December 25
Christmas Day is the single biggest closure day for chain pharmacies in the United States. Most stores close entirely; a small subset of 24-hour CVS and Walgreens locations stay open with limited pharmacy service.
See all chains →the fourth Thursday of November
Thanksgiving is the second-largest closure day. Most pharmacy counters are closed; some 24-hour drugstores keep front-store hours but the pharmacy itself is dark.
See all chains →January 1
New Year's Day is a partial closure day. Most chains operate on Sunday or shortened holiday hours; pharmacy counters typically open later and close earlier than the front store.
See all chains →a moveable date in late March or April
Easter Sunday sees most pharmacies open with Sunday or shortened holiday hours. Costco is the major exception — every warehouse and pharmacy is closed.
See all chains →the last Monday of May
Memorial Day operates on holiday hours at most chains. The major retail pharmacies stay open with regular or slightly reduced schedules; Costco closes entirely.
See all chains →the first Monday of September
Labor Day is treated similarly to Memorial Day — most chains keep regular Monday hours, Costco closes warehouses and pharmacies.
See all chains →July 4
Independence Day is a normal operating day at most national pharmacy chains, with a few stores opting for slightly reduced hours. Costco is closed; everyone else is open.
See all chains →Every page reflects each chain's published store-locator data and corporate holiday calendar. We re-check ahead of every major holiday and update what's changed.
We document each chain's actual savings program — ExtraCare, myWalgreens, Walmart+ Rx for Less, the Costco Member Prescription Program, Kroger Rx Savings Club, and Publix's free generics — not paid affiliate promo codes.
If your question is "is this pharmacy open right now," every page is structured to answer that first, with the holiday and city detail underneath.