South Carolina

CVS Pharmacy in South Carolina

CVS operates throughout South Carolina. Standard hours, holiday schedules, and the largest city-level locators.

CVS South Carolina hours

Store frontMonday–Friday 7:00am–10:00pm, Saturday 8:00am–10:00pm, Sunday 9:00am–9:00pm
Pharmacy counterMonday–Friday 9:00am–9:00pm, Saturday 9:00am–6:00pm, Sunday 10:00am–6:00pm

CVS stores in South Carolina follow the chain-wide hours above as a default. Individual locations adjust based on local market demand — urban-core stores in South Carolina typically open earlier and stay open later than suburban stores. The official CVS store locator publishes the exact hours for each South Carolina location and is the source of truth for any specific store.

CVS holiday hours in South Carolina

CVS South Carolina locations follow the national holiday calendar. CVS operates several hundred 24-hour locations clustered in major metros (Los Angeles, Chicago, Houston, Phoenix, Atlanta, Las Vegas, Miami, New York). The 24-hour designation usually applies to the front store; the pharmacy counter still keeps standard daytime hours at most of those sites.

Christmas DayClosed at standalone CVS locations; limited service at 24-hour pharmacies in major metros
ThanksgivingMost pharmacy counters closed; 24-hour pharmacies open with reduced staffing
New Year's DaySunday pharmacy hours observed
Easter SundaySunday pharmacy hours observed
Memorial DayRegular weekday pharmacy hours
Labor DayRegular weekday pharmacy hours
Independence DayRegular weekday pharmacy hours

CVS locations across South Carolina

To find specific CVS locations across South Carolina, use the CVS Pharmacy store locator. Search by ZIP code or city to see real-time pharmacy hours and 24-hour status for each store.

ExtraCare in South Carolina

ExtraCare is CVS's free loyalty program. Members earn 2% back in ExtraBucks Rewards on most purchases plus quarterly ExtraBucks based on prescription pickups, and unlock weekly digital coupons in the CVS app. The same program applies at every CVS South Carolina location. Read the full ExtraCare guide →

Other chains in South Carolina