South Dakota

Publix Pharmacy in South Dakota

Publix Pharmacy operates throughout South Dakota. Standard hours, holiday schedules, and the largest city-level locators.

Publix Pharmacy South Dakota hours

Store frontMonday–Saturday 7:00am–10:00pm, Sunday 7:00am–10:00pm
Pharmacy counterMonday–Friday 9:00am–9:00pm, Saturday 9:00am–7:00pm, Sunday 11:00am–6:00pm

Publix Pharmacy stores in South Dakota follow the chain-wide hours above as a default. Individual locations adjust based on local market demand — urban-core stores in South Dakota typically open earlier and stay open later than suburban stores. The official Publix Pharmacy store locator publishes the exact hours for each South Dakota location and is the source of truth for any specific store.

Publix Pharmacy holiday hours in South Dakota

Publix Pharmacy South Dakota locations follow the national holiday calendar. Publix does not operate 24-hour stores. Pharmacy counters close one hour before the surrounding store and are closed by 6pm on Sunday.

Christmas DayClosed
ThanksgivingClosed
New Year's DayReduced hours, typically 10:00am–5:00pm
Easter SundayPharmacy 11:00am–6:00pm
Memorial DayRegular weekday pharmacy hours
Labor DayRegular weekday pharmacy hours
Independence DayRegular weekday pharmacy hours

Publix Pharmacy locations across South Dakota

To find specific Publix Pharmacy locations across South Dakota, use the Publix Pharmacy store locator. Search by ZIP code or city to see real-time pharmacy hours and 24-hour status for each store.

Publix Pharmacy Free Medication Program in South Dakota

Publix Pharmacy fills several common medications free of charge with a valid prescription, including up to a 90-day supply of metformin (immediate-release), lisinopril, amlodipine, and the generic versions of amoxicillin, ampicillin, ciprofloxacin, penicillin VK, sulfamethoxazole/trimethoprim, and more. The same program applies at every Publix Pharmacy South Dakota location. Read the full Publix Pharmacy Free Medication Program guide →

Other chains in South Dakota